Joint analysis of left-censored longitudinal biomarker and binary outcome via latent class modeling.
Sign Up to like & getrecommendations! Published in 2018 at "Statistics in medicine"
DOI: 10.1002/sim.7642
Abstract: Joint latent class modeling is an appealing approach for evaluating the association between a longitudinal biomarker and clinical outcome when the study population is heterogeneous. The link between the biomarker trajectory and the risk of event… read more here.
Keywords: outcome; biomarker; longitudinal biomarker; latent class ... See more keywords
Estimation of the distribution of longitudinal biomarker trajectories prior to disease progression.
Sign Up to like & getrecommendations! Published in 2019 at "Statistics in medicine"
DOI: 10.1002/sim.8085
Abstract: Most studies characterize longitudinal biomarker trajectories by looking forward at them from a commonly used time origin, such as the initial treatment time. For a better understanding of the relationship between biomarkers and disease progression,… read more here.
Keywords: biomarker; time; longitudinal biomarker; disease ... See more keywords
Initial Data and a Clinical Diagnosis Transition for the Aiginition Longitudinal Biomarker Investigation of Neurodegeneration (ALBION) Study
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina58091179
Abstract: Background and Objectives: This article presents data from the ongoing Aiginition Longitudinal Biomarker Investigation of Neurodegeneration study (ALBION) regarding baseline clinical characterizations and CSF biomarker profiles, as well as preliminary longitudinal data on clinical progression.… read more here.
Keywords: longitudinal biomarker; mci; biomarker; aiginition longitudinal ... See more keywords