Longitudinal monitoring by next‐generation sequencing of plasma cell‐free DNA in ALK rearranged NSCLC patients treated with ALK tyrosine kinase inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4663
Abstract: Patients with ALK‐rearranged non‐small cell lung cancer (ALK+ NSCLC) inevitably acquire resistance to ALK inhibitors. Longitudinal monitoring of cell‐free plasma DNA (cfDNA) next‐generation sequencing (NGS) could predict the response and resistance to tyrosine kinase inhibitor… read more here.
Keywords: cell; alk rearranged; cell free; next generation ... See more keywords
Longitudinal Monitoring of Progressive Supranuclear Palsy using Body‐Worn Movement Sensors
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DOI: 10.1002/mds.29194
Abstract: We have previously shown that wearable technology and machine learning techniques can accurately discriminate between progressive supranuclear palsy (PSP), Parkinson's disease, and healthy controls. To date these techniques have not been applied in longitudinal studies… read more here.
Keywords: monitoring progressive; movement; progressive supranuclear; longitudinal monitoring ... See more keywords
Longitudinal monitoring of ctDNA EGFR mutation burden from urine correlates with patient response to EGFR TKIs: A case series.
Sign Up to like & getrecommendations! Published in 2017 at "Lung cancer"
DOI: 10.1016/j.lungcan.2017.02.010
Abstract: Targetable, somatic EGFR mutations are highly prevalent in patients with non-small cell lung cancer (NSCLC), making them eligible for tyrosine kinase inhibitor (TKI) therapy. Circulating tumor DNA (ctDNA), isolated from blood or urine, has been… read more here.
Keywords: longitudinal monitoring; egfr; ctdna; response ... See more keywords
Longitudinal Monitoring of Gd-DTPA Following Convection Enhanced Delivery in the Brainstem.
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DOI: 10.1016/j.wneu.2020.01.199
Abstract: BACKGROUND Convection-enhanced delivery (CED) has been introduced into contemporary therapeutic strategies for incurable brain neoplasms as diffuse intrinsic pontine glioma (DIPG). Therapeutic benefit in part is predictably dependent upon drug distribution within tumor. However, therapeutics… read more here.
Keywords: longitudinal monitoring; dtpa; convection enhanced; monitoring ... See more keywords
A bioluminescent probe for longitudinal monitoring of mitochondrial membrane potential
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DOI: 10.1038/s41589-020-0602-1
Abstract: Mitochondrial membrane potential (Δ Ψ m ) is a universal selective indicator of mitochondrial function and is known to play a central role in many human pathologies, such as diabetes mellitus, cancer and Alzheimer’s and… read more here.
Keywords: longitudinal monitoring; probe; bioluminescent probe; membrane potential ... See more keywords
Unusual total anti-SARS-CoV-2 antibody kinetics observed during longitudinal monitoring after BNT162b2 vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2123388
Abstract: Abstract The present study aimed to clarify unusual total antibody kinetics in three female individuals observed during longitudinal monitoring of antibody response to BNT162b2 COVID-19 vaccine in 54 healthy volunteers. Total and IgG antibodies against… read more here.
Keywords: unusual total; antibody kinetics; antibody; observed longitudinal ... See more keywords
Longitudinal monitoring of neutral and adaptive genomic diversity in a reintroduction
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DOI: 10.1111/cobi.13889
Abstract: Restoration programs in the form of ex‐situ breeding combined with reintroductions are becoming critical to counteract demographic declines and species losses. Such programs are increasingly using genetic management to improve conservation outcomes. However, the lack… read more here.
Keywords: reintroduction; genomic diversity; breeding; adaptive genomic ... See more keywords
Non‐invasive longitudinal monitoring of angiogenesis in a murine full‐thickness cutaneous wound healing model using high‐resolution three‐dimensional ultrasound imaging
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DOI: 10.1111/srt.12374
Abstract: The aim of this study was to evaluate the longitudinal monitoring of angiogenesis in a murine full‐thickness cutaneous wound healing model using high‐resolution three‐dimensional (3D) ultrasound imaging. read more here.
Keywords: longitudinal monitoring; angiogenesis murine; full thickness; murine full ... See more keywords
Longitudinal monitoring by next generation sequencing of plasma cell-free DNA in ALK-rearranged non-small cell lung cancer (NSCLC) patients treated with ALK tyrosine kinase inhibitors.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.9603
Abstract: 9603Background: Patients with anaplastic lymphoma kinase-rearranged (ALK+) NSCLC inevitably acquire resistance to ALK inhibitors. We hypothesized that longitudinal monitoring of cell-free plasma DN... read more here.
Keywords: longitudinal monitoring; nsclc; alk; kinase ... See more keywords