Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs
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DOI: 10.1038/s41598-018-34084-5
Abstract: Impairment of the ubiquitin proteasome system has been implicated in Parkinson’s disease. We used positron emission tomography to investigate longitudinal effects of chronic intracerebroventricular exposure to the proteasome inhibitor lactacystin on monoaminergic projections and neuroinflammation.… read more here.
Keywords: proteasome inhibition; pet imaging; longitudinal monoaminergic; chronic proteasome ... See more keywords