LAUSR

Coordination‐Responsive Longitudinal Relaxation Tuning as a Versatile MRI Sensing Protocol for Malignancy Targets

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0 Published in 2018 at "Advanced Science"

DOI: 10.1002/advs.201800021

Abstract: Abstract Biomarkers (e.g., acidity, H2O2, hypoxia, and specific molecules) as one primary component of tumor microenvironments are closely associated with occurrence, invasion, and metastasis of malignancy, thus can act as biological targets. However, their monitoring… read more here.

Keywords: coordination; longitudinal relaxation; relaxation tuning; malignancy ... See more keywords

White matter microstructure and longitudinal relaxation time anisotropy in human brain at 3 and 7 T

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2 Published in 2022 at "Nmr in Biomedicine"

DOI: 10.1002/nbm.4815

Abstract: A high degree of structural order by white matter (WM) fibre tracts creates a physicochemical environment where water relaxations are rendered anisotropic. Recently, angularly dependent longitudinal relaxation has been reported in human WM. We have… read more here.

Keywords: white matter; longitudinal relaxation; relaxation; broad peak ... See more keywords

Simultaneous estimation of cellular water exchange rate, intracellular volume fraction, and longitudinal relaxation rate in cancer cells.

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1 Published in 2023 at "NMR in biomedicine"

DOI: 10.1002/nbm.4914

Abstract: PURPOSE To investigate the feasibility of simultaneously estimating cellular water efflux rate (kie ), intracellular longitudinal relaxation rate (R10i ) and intracellular volume fraction (vi ) of a cell suspension using multiple samples with different… read more here.

Keywords: longitudinal relaxation; rate; cellular water; estimation ... See more keywords

Repeatability and reproducibility of longitudinal relaxation rate in 12 small-animal MRI systems

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0 Published in 2019 at "Magnetic Resonance Imaging"

DOI: 10.1016/j.mri.2019.03.008

Abstract: Background Many translational MR biomarkers derive from measurements of the water proton longitudinal relaxation rate R1, but evidence for between-site reproducibility of R1 in small-animal MRI is lacking. Objective To assess R1 repeatability and multi-site… read more here.

Keywords: small animal; longitudinal relaxation; repeatability; reproducibility ... See more keywords

Analyzing the sensitivity of quantitative 3D MRI of longitudinal relaxation at very low field in Gd-doped phantoms

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2 Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0285391

Abstract: Purpose Recently, new MRI systems working at magnetic field below 10 mT (Very and Ultra Low Field regime) have been developed, showing improved T1-contrast in projected 2D maps (i.e. images without slice selection). Moving from… read more here.

Keywords: low field; sensitivity; contrast; longitudinal relaxation ... See more keywords