Articles with "lonidamine conjugated" as a keyword



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Cu(I) and Cu(II) Complexes Based on Lonidamine-Conjugated Ligands Designed to Promote Synergistic Antitumor Effects

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Published in 2022 at "Inorganic Chemistry"

DOI: 10.1021/acs.inorgchem.1c03658

Abstract: Bis(pyrazol-1-yl)- and bis(3,5-dimethylpyrazol-1-yl)-acetates were conjugated with the 2-hydroxyethylester and 2-aminoethylamide derivatives of the antineoplastic drug lonidamine to prepare Cu(I) and Cu(II) complexes that might act through synergistic mechanisms of action due to the presence of… read more here.

Keywords: complexes based; conjugated ligands; antitumor; based lonidamine ... See more keywords