Durability of Clinical and Quality-of-Life Outcomes of Closed-Loop Spinal Cord Stimulation for Chronic Back and Leg Pain: A Secondary Analysis of the Evoke Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2021.4998
Abstract: Importance Chronic pain is debilitating and profoundly affects health-related quality of life. Spinal cord stimulation (SCS) is a well-established therapy for chronic pain; however, SCS has been limited by the inability to directly measure the… read more here.
Keywords: back leg; loop; scs; leg pain ... See more keywords
Targeting Tumor Heterogeneity by Breaking a Stem Cell and Epithelial Niche Interaction Loop
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202307452
Abstract: Tumor heterogeneity, the presence of multiple distinct subpopulations of cancer cells between patients or among the same tumors, poses a major challenge to current targeted therapies. The way these different subpopulations interact among themselves and… read more here.
Keywords: tumor heterogeneity; niche; stem; loop ... See more keywords
Effect of G-quadruplex loop mutations on the G-quadruplex formation, protein binding and transcription of BmPOUM2 in Bombyx mori.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21876
Abstract: A G-quadruplex (G4) was identified in the promoter of transcription factor BmPOUM2 in Bombyx mori. This G4 structure contains three loops and is bound by transcription factor BmLARK, facilitating the transcription of BmPOUM2. However, the… read more here.
Keywords: bmpoum2 bombyx; loop; structure; transcription ... See more keywords
In through the out door: A loop‐binding‐first model for topological cohesin loading
Sign Up to like & getrecommendations! Published in 2024 at "BioEssays"
DOI: 10.1002/bies.202400120
Abstract: Cohesin is a ring‐shaped complex that is loaded on DNA in two different conformations. In one conformation, it forms loops to organize the interphase genome; in the other, it topologically encircles sibling chromosomes to facilitate… read more here.
Keywords: binding first; loop; loop binding; first model ... See more keywords
The use of thiazide and thiazide‐like diuretics in heart failure with congestion
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1455
Abstract: We read with great interest the article of Mullens et al.1 about the practical use of diuretics in patients with acute and chronic heart failure (HF). Surprisingly, there is still little evidence about the use… read more here.
Keywords: use; loop diuretic; heart failure; loop ... See more keywords
circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.12859
Abstract: BACKGROUND Circular RNAs (circRNAs) represent a novel class of non-coding RNAs formed by a covalently closed loop and play crucial roles in many biological processes. Several circRNAs associated with myogenesis have been reported. However, the… read more here.
Keywords: skeletal muscle; muscle regeneration; muscle; loop ... See more keywords
Efficiently train and validate a RapidPlan model through APQM scoring
Sign Up to like & getrecommendations! Published in 2018 at "Medical Physics"
DOI: 10.1002/mp.12896
Abstract: PURPOSE The aim of this study was to propose and validate an intuitive method for training and to validate knowledge-based planning (KBP) systems based on a patient-specific plan quality scoring. METHODS A sample of 80… read more here.
Keywords: quality; plan quality; model; loop ... See more keywords
Development of charybdotoxin Q18F variant as a selective peptide blocker of neuronal BK(α + β4) channel for the treatment of epileptic seizures
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4506
Abstract: Epilepsy is the results from the imbalance between inhibition and excitation in neural circuits, which is mainly treated by some chemical drugs with side effects. Gain‐of‐function of BK channels or knockout of its β4 subunit… read more here.
Keywords: q18f variant; charybdotoxin; loop; charybdotoxin q18f ... See more keywords
Higher order RG flow on the Wilson line in N $$ \mathcal{N} $$ = 4 SYM
Sign Up to like & getrecommendations! Published in 2022 at "Journal of High Energy Physics"
DOI: 10.1007/jhep01(2022)056
Abstract: Extending earlier work, we find the two-loop term in the beta-function for the scalar coupling ζ in a generalized Wilson loop operator of the N $$ \mathcal{N} $$ = 4 SYM theory, working in the… read more here.
Keywords: beta function; wilson loop; loop; wilson ... See more keywords
Weyl fermion creation by cosmological gravitational wave background at 1-loop
Sign Up to like & getrecommendations! Published in 2024 at "Journal of High Energy Physics"
DOI: 10.1007/jhep01(2025)023
Abstract: Weyl fermions of spin 12\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ \frac{1}{2} $$\end{document} minimally coupled to Einstein’s gravity in 4 dimensions cannot be produced purely gravitationally in an expanding Universe at tree… read more here.
Keywords: gravitational wave; wave; loop; wave background ... See more keywords
Double scaling limit of N$$ \mathcal{N} $$= 2 chiral correlators with Maldacena-Wilson loop
Sign Up to like & getrecommendations! Published in 2019 at "Journal of High Energy Physics"
DOI: 10.1007/jhep02(2019)095
Abstract: A bstractWe consider N$$ \mathcal{N} $$ = 2 conformal QCD in four dimensions and the one-point correlator of a class of chiral primaries with the circular 12$$ \frac{1}{2} $$-BPS Maldacena-Wilson loop. We analyze a recently… read more here.
Keywords: maldacena wilson; wilson loop; limit; loop ... See more keywords