CENP-C-Mis12 complex establishes a regulatory loop through Aurora B for chromosome segregation
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DOI: 10.26508/lsa.202402927
Abstract: Generating various CENP-C mutant cell lines, Kong et al demonstrated that there is a positive regulatory loop between Aurora B recruitment and the CENP-C-Mis12C interaction at kinetochores in mammalian cells. Establishing the correct kinetochore–microtubule attachment… read more here.
Keywords: cenp; loop aurora; regulatory loop; chromosome segregation ... See more keywords
Phosphorylation, Mg-ADP, and Inhibitors Differentially Shape the Conformational Dynamics of the A-Loop of Aurora-A
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DOI: 10.3390/biom11040567
Abstract: The conformational state of the activation loop (A-loop) is pivotal for the activity of most protein kinases. Hence, the characterization of the conformational dynamics of the A-loop is important to increase our understanding of the… read more here.
Keywords: conformational dynamics; dynamics loop; loop aurora; phosphorylation adp ... See more keywords