PKD autoinhibition in trans regulates activation loop autophosphorylation in cis
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DOI: 10.1101/2022.05.05.490744
Abstract: Phosphorylation is a ubiquitous mechanism by which signals are transduced in cells. Protein kinases, enzymes that catalyze the phospho-transfer reaction are, themselves, often regulated by phosphorylation. Paradoxically, however, a substantial fraction of the more than… read more here.
Keywords: activation loop; phosphorylation; activation; loop autophosphorylation ... See more keywords