Effectiveness and safety of combining thiazides with loop diuretics vs. loop diuretics monotherapy in patients with acute decompensated heart failure: A retrospective cohort study.
Sign Up to like & getrecommendations! Published in 2025 at "British journal of clinical pharmacology"
DOI: 10.1002/bcp.70257
Abstract: This study investigated factors associated with and outcomes of combined loop diuretics with hydrochlorothiazide (HCTZ) for acute decompensated heart failure (ADHF). read more here.
Keywords: decompensated heart; acute decompensated; loop diuretics; study ... See more keywords
Use of short‐acting vs. long‐acting loop diuretics after heart failure hospitalization
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DOI: 10.1002/ehf2.14030
Abstract: Furosemide, a short‐acting loop diuretic (SD), is the dominant agent prescribed for heart failure (HF) in clinical practice. However, accumulating data suggests that long‐acting loop diuretics (LD), such as torsemide or azosemide, might have more… read more here.
Keywords: acting loop; loop diuretics; heart failure;
Evaluation of the short-term echocardiographic effects of two loop diuretics, furosemide and torsemide, in a group of dogs.
Sign Up to like & getrecommendations! Published in 2023 at "Veterinary medicine and science"
DOI: 10.1002/vms3.1129
Abstract: BACKGROUND Two loop diuretics, torsemide and frusemide, can affect the urinary system and consequently the cardiordiovascular haemodynamics in different ways. OBJECTIVES This study compared a number of echocardiographic parameters and systemic arterial blood pressure (ABP)… read more here.
Keywords: loop diuretics; two loop; blood pressure; furosemide torsemide ... See more keywords
Diuretic Treatment in Patients with Heart Failure: Current Evidence and Future Directions – Part I: Loop Diuretics
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DOI: 10.1007/s11897-024-00643-3
Abstract: Fluid retention or congestion is a major cause of symptoms, poor quality of life, and adverse outcome in patients with heart failure (HF). Despite advances in disease-modifying therapy, the mainstay of treatment for congestion—loop diuretics—has… read more here.
Keywords: loop diuretics; treatment; heart failure; diuretic treatment ... See more keywords
Clinical Pharmacology of Loop Diuretics in Critical Care
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DOI: 10.1007/s40262-025-01524-1
Abstract: Loop diuretics are a cornerstone in the management of fluid overload in critically ill patients; however, their use is often complicated by variable pharmacokinetics and the phenomenon of diuretic resistance. This narrative review comprehensively examines… read more here.
Keywords: loop diuretics; pharmacology; critical care; diuretic resistance ... See more keywords
Fluorescent detection of loop diuretics by sensors based on zinc(II) bis(dipyrromethenate)s
Sign Up to like & getrecommendations! Published in 2020 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2020.108389
Abstract: Abstract This paper is a follow-up to our recent study of the zinc(II) bis(dipyrromethenate)s ([Zn2L2]s) sensory capabilities for furosemide detection. We complement our studies with the results of torasemide fluorescent detection by [Zn2L2]s with 0.037–0.11 μg mL−1… read more here.
Keywords: detection; fluorescent detection; zinc bis; loop diuretics ... See more keywords
Loop diuretics are K+-sparing in the presence of a low-Na+, high-K+ diet.
Sign Up to like & getrecommendations! Published in 2017 at "Kidney international"
DOI: 10.1016/j.kint.2017.05.022
Abstract: Under most conditions, loop diuretics are K+-wasting, requiring potassium supplementation. In this issue, Wang and colleagues demonstrate that in mice fed a low-Na+, high-K+ diet, loop diuretics, in contrast, are K+-sparing. This observation suggests that possible elevations… read more here.
Keywords: high diet; low high; diet loop; loop diuretics ... See more keywords
Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B
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DOI: 10.1038/s41598-018-27995-w
Abstract: The Na+–K+–2Cl− cotransporter NKCC1 plays a role in neuronal Cl− homeostasis secretion and represents a target for brain pathologies with altered NKCC1 function. Two main variants of NKCC1 have been identified: a full-length NKCC1 transcript… read more here.
Keywords: loop diuretics; cotransporter; potent bumetanide; azosemide potent ... See more keywords
Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study
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DOI: 10.1136/heartjnl-2023-323577
Abstract: Background Loop diuretics are commonly prescribed in the community, not always to patients with a recorded diagnosis of heart failure (HF). The rate of HF events in patients prescribed loop diuretics without a diagnosis of… read more here.
Keywords: diagnosis; heart; loop diuretic; group ... See more keywords
Abstract 12968: Impact of Loop Diuretics Use on Skeletal Muscle Depletion Among Patients Being Evaluated for Known or Suspected Coronary Artery Disease a Propensity Score Matching Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.12968
Abstract: Background: It is well known that sarcopenia worsens the prognosis among patients with heart failure (HF). Causes and incidence of sarcopenia in patients with HF have become more important because of the increasing number of… read more here.
Keywords: muscle; loop diuretics; skeletal muscle; diuretics use ... See more keywords
Effect of dapagliflozin on readmission and loop diuretics use in patients with acute heart failure: a retrospective propensity score-matched cohort study
Sign Up to like & getrecommendations! Published in 2024 at "BMC Cardiovascular Disorders"
DOI: 10.1186/s12872-024-04078-5
Abstract: The efficacy of dapagliflozin in patients with acute heart failure remains unclear. To investigate the impact of dapagliflozin (DAPA) on loop diuretics use and 90-day readmission in patients with acute heart failure. In a retrospective… read more here.
Keywords: heart; loop diuretics; heart failure; acute heart ... See more keywords