Common Patterns of Hydrolysis Initiation in P-loop Fold Nucleoside Triphosphatases
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DOI: 10.3390/biom12101345
Abstract: The P-loop fold nucleoside triphosphate (NTP) hydrolases (also known as Walker NTPases) function as ATPases, GTPases, and ATP synthases, are often of medical importance, and represent one of the largest and evolutionarily oldest families of… read more here.
Keywords: loop fold; loop ntpases; loop; fold nucleoside ... See more keywords
Common Mechanism of Activated Catalysis in P-loop Fold Nucleoside Triphosphatases—United in Diversity
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101346
Abstract: To clarify the obscure hydrolysis mechanism of ubiquitous P-loop-fold nucleoside triphosphatases (Walker NTPases), we analysed the structures of 3136 catalytic sites with bound Mg-NTP complexes or their analogues. Our results are presented in two articles;… read more here.
Keywords: loop fold; fold nucleoside; loop; ser thr ... See more keywords