Articles with "loop loop" as a keyword



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Successful Manipulation of the Product Spectrum of the Erwinia amylovora Levansucrase by Modifying the Residues around loop1, Loop 3, and Loop 4.

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Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c07891

Abstract: Levansucrase (LS, EC 2.4.1.10) catalyzes the synthesis of levan by successively transferring the fructosyl moiety from sucrose to an elongated fructan chain. Although the product distribution of LS from Erwinia amylovora (Ea-LS) was studied under… read more here.

Keywords: erwinia amylovora; loop; levansucrase; product spectrum ... See more keywords
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Discovery of Cysteine-targeting Covalent Protein Kinase Inhibitors.

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Published in 2021 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.1c01719

Abstract: Small molecule covalent kinase inhibitors (CKIs) have entered a new era in drug discovery, which have the advantage for sustained target inhibition and high selectivity. An increased understanding of binding kinetics of CKIs and discovery… read more here.

Keywords: chemistry; kinase inhibitors; loop loop; cysteine ... See more keywords