Closed-loop neuromodulation in an individual with treatment-resistant depression.
Sign Up to like & getrecommendations! Published in 2021 at "Nature medicine"
DOI: 10.1038/s41591-021-01480-w
Abstract: Deep brain stimulation is a promising treatment for neuropsychiatric conditions such as major depression. It could be optimized by identifying neural biomarkers that trigger therapy selectively when symptom severity is elevated. We developed an approach… read more here.
Keywords: depression; loop neuromodulation; depression closed; stimulation ... See more keywords
Closed-loop neuromodulation systems: next-generation treatments for psychiatric illness
Sign Up to like & getrecommendations! Published in 2017 at "International Review of Psychiatry"
DOI: 10.1080/09540261.2017.1282438
Abstract: Abstract Despite deep brain stimulation’s positive early results in psychiatric disorders, well-designed clinical trials have yielded inconsistent clinical outcomes. One path to more reliable benefit is closed-loop therapy: stimulation that is automatically adjusted by a… read more here.
Keywords: neuromodulation systems; loop neuromodulation; psychiatric illness; neuromodulation ... See more keywords
Closed-Loop Neuromodulation in Physiological and Translational Research.
Sign Up to like & getrecommendations! Published in 2018 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a034314
Abstract: Neuromodulation, the focused delivery of energy to neural tissue to affect neural or physiological processes, is a common method to study the physiology of the nervous system. It is also successfully used as treatment for… read more here.
Keywords: loop neuromodulation; system; translational research; physiological translational ... See more keywords
Closed-Loop Implantable Therapeutic Neuromodulation Systems Based on Neurochemical Monitoring
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00808
Abstract: Closed-loop or intelligent neuromodulation allows adjustable, personalized neuromodulation which usually incorporates the recording of a biomarker, followed by implementation of an algorithm which decides the timing (when?) and strength (how much?) of stimulation. Closed-loop neuromodulation… read more here.
Keywords: loop neuromodulation; biomarker; neuromodulation; closed loop ... See more keywords