Influence of the loop size and nucleotide composition on AgoshRNA biogenesis and activity
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DOI: 10.1080/15476286.2017.1328349
Abstract: ABSTRACT Short hairpin RNAs (shRNAs) are widely used for gene silencing by the RNA interference (RNAi) mechanism. The shRNA precursor is processed by the Dicer enzyme into active small interfering RNAs (siRNAs) that subsequently target… read more here.
Keywords: loop size; influence loop; agoshrna; activity ... See more keywords