Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis
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DOI: 10.1002/advs.202103228
Abstract: Conventional antiplatelet agents indiscriminately inhibit both thrombosis and hemostasis, and the increased bleeding risk thus hampers their use at more aggressive dosages to achieve adequate effect. Blocking integrin αIIbβ3 outside‐in signaling by separating the β3/Src… read more here.
Keywords: hemostasis; thrombosis; loop src; src sh3 ... See more keywords