SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts.
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DOI: 10.1016/j.molcel.2020.05.011
Abstract: Many microRNAs (miRNAs) are generated from primary transcripts containing multiple clustered stem-loop structures that are thought to be recognized and cleaved by the Microprocessor complex as independent units. Here, we uncover an unexpected mode of… read more here.
Keywords: mirna; processing suboptimal; loop structures; stem loop ... See more keywords
Stem–Loop Structures in Iron-Regulated mRNAs of Giardia duodenalis
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DOI: 10.3390/ijerph20043556
Abstract: Giardia duodenalis is a significant cause of waterborne and foodborne infections, day-care center outbreaks, and traveler’s diarrhea worldwide. In protozoa such as Trichomonas vaginalis and Entamoeba histolytica, iron affects the growth, pathogenicity mechanisms, and expression… read more here.
Keywords: stem loop; iron; mrnas giardia; loop structures ... See more keywords