Do antibody CDR loops change conformation upon binding?
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DOI: 10.1080/19420862.2024.2322533
Abstract: ABSTRACT Antibodies have increasingly been developed as drugs with over 100 now licensed in the US or EU. During development, it is often necessary to increase or reduce the affinity of an antibody and rational… read more here.
Keywords: change conformation; antibody; antigen; loops change ... See more keywords