Articles with "loperamide vitro" as a keyword



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Functional characteristics of CYP3A4 allelic variants on the metabolism of loperamide in vitro

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Published in 2019 at "Infection and Drug Resistance"

DOI: 10.2147/idr.s215129

Abstract: Background Cytochrome P450 3A4 (CYP3A4) appears to be genetically polymorphic, which in turn contributes to interindividual variability in response to therapeutic drugs. Loperamide, identified as a CYP3A4 substrate, is prone to misuse and abuse and… read more here.

Keywords: cyp3a4 variants; functional characteristics; characteristics cyp3a4; cyp3a4 ... See more keywords