NSAIDs for Prophylaxis for Heterotopic Ossification After Total Hip Arthroplasty: A Bayesian Network Meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "Calcified Tissue International"
DOI: 10.1007/s00223-020-00763-7
Abstract: Non-steroidal anti-inflammatory drugs (NSAID) have been recommended to prevent of heterotopic ossification (HO) after total hip arthroplasty (THA), but debates are still ongoing. The present Bayesian network meta-analysis of randomized clinical trials (RCTs) compared all… read more here.
Keywords: network; bayesian network; analysis; lor ... See more keywords
Better Late than Never: Adding Thiopurines After Loss of Response to Infliximab Monotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06681-w
Abstract: Since infliximab (IFX), a monoclonal antibody that specifically targets tumor necrosis factor (TNF), is efficacious and safe in the treatment for Crohn’s disease (CD), IFX therapy has become a popular choice for the induction and… read more here.
Keywords: disease; lor; thiopurine; therapy ... See more keywords
Exploring the gender gap: Letters of recommendation to pediatric surgery fellowship.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of surgery"
DOI: 10.1016/j.amjsurg.2019.08.005
Abstract: BACKGROUND Letters of recommendation (LoR) are considered one of the most important predictors of matching into a pediatric surgery fellowship. We determined if gendered differences exist in LoR written for resident candidates. METHODS A retrospective… read more here.
Keywords: surgery; letters recommendation; surgery fellowship; pediatric surgery ... See more keywords
Spontaneous recovery of traumatic brain injury-induced functional deficits is not hindered by daily administration of lorazepam
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DOI: 10.1016/j.bbr.2017.11.039
Abstract: HIGHLIGHTSThree doses of lorazepam (LOR) were chronically administered after TBI and none impaired functional recovery.LOR at 2.0 mg/kg enhanced motor function after TBI.LOR at 2.0 mg/kg enhanced spatial learning after TBI.LOR at any dose did… read more here.
Keywords: recovery; traumatic brain; lor; tbi ... See more keywords
Implementation of Neural Networks to Frontal Electroencephalography for the Identification of the Transition Responsiveness/Unresponsiveness During Induction of General Anesthesia
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DOI: 10.1016/j.irbm.2021.02.004
Abstract: Abstract Objective General anesthesia is a reversible drug-induced state of altered arousal characterized by loss of responsiveness (LOR) due to brainstem inactivation. Precise identification of the LOR during the induction of general anesthesia is extremely… read more here.
Keywords: general anesthesia; lor; responsiveness; induction general ... See more keywords
Letters of recommendation for pediatric surgery fellowship: Analysis of linguistic differences based on gender of the applicant.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2021.02.049
Abstract: BACKGROUND Gender bias in letters of recommendation (LOR) has been reported for candidate selection in academic medicine, typically with females frequently described with communal terms (e.g. helpful, kind, interpersonal) and males described more with agentic… read more here.
Keywords: medicine; surgery fellowship; pediatric surgery; gender ... See more keywords
DOP75 Loss-of-response and immunogenicity following immunomodulator withdrawal from anti-tumour necrosis factor alpha combination therapy: Results from a large retrospective cohort study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab073.114
Abstract: Combination therapy with anti-TNF compounds and immunomodulators (IMM; thiopurine or methotrexate) is superior to IMM or anti-TNF monotherapy in patients with inflammatory bowel disease (IBD). IMMs are frequently discontinued during the maintenance phase to mitigate… read more here.
Keywords: lor; combination therapy; imm; withdrawal ... See more keywords
FRI0430 THE NOVEL, INTRA-ARTICULAR CLK/DYRK1A INHIBITOR LORECIVIVINT (LOR; SM04690), WHICH MODULATES THE WNT PATHWAY, IMPROVED RESPONDER OUTCOMES IN SUBJECTS WITH KNEE OSTEOARTHRITIS: A POST HOC ANALYSIS FROM A PHASE 2B TRIAL
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.6467
Abstract: Background: Lorecivivint (LOR; SM04690) is a small-molecule, intra-articular (IA) CLK/DYRK1A inhibitor that modulates the Wnt pathway1 and has demonstrated some beneficial effects on patient-reported outcomes (PROs) relative to placebo (PBO) in two Phase 2 knee… read more here.
Keywords: samumed llc; lor; phase; post hoc ... See more keywords
Durability of Initial Platelet Count Response in Patients Treated with Avatrombopag for Immune Thrombocytopenia (ITP): Post-Hoc Results from a Phase 3 Clinical Study
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DOI: 10.1182/blood-2020-142764
Abstract: Background: The clinical management of ITP has been evolving. Thrombopoietin receptor agonists (TPO-RAs) have become widely utilized as subsequent treatments, and the 2019 ASH guidelines recommend their use over rituximab to achieve a durable response.… read more here.
Keywords: response; study; lor; itp ... See more keywords
Determination of Loratadine and Its Active Metabolite in Plasma by LC/MS/MS: An Adapted Method for Children
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DOI: 10.2174/1573412915666190416121233
Abstract: Loratadine (LOR) (Fig. 1), an active H1 receptor antagonist, is often used in the treatment of allergic disorders such as seasonal allergies and skin rash [1]. LOR was clinically approved for symptomatic relief of nasal… read more here.
Keywords: active metabolite; determination loratadine; plasma; adapted method ... See more keywords
A new pressure guided management tool for epidural space detection: feasibility assessment in a clinical scenario.
Sign Up to like & getrecommendations! Published in 2020 at "Minerva anestesiologica"
DOI: 10.23736/s0375-9393.20.14031-8
Abstract: BACKGROUND The detection of epidural space is usually performed by the technique of loss of resistance (LOR) without technological support, although there are few commercial options. In this work, we aimed to assess the feasibility… read more here.
Keywords: system; lor; pressure; epidural space ... See more keywords