Articles with "lorlatinib attenuates" as a keyword



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Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade

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Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-23731-7

Abstract: Pancreatic ductal adenocarcinoma (PDAC) patients have a 5-year survival rate of only 8% largely due to late diagnosis and insufficient therapeutic options. Neutrophils are among the most abundant immune cell type within the PDAC tumor… read more here.

Keywords: tumor associated; associated neutrophils; cancer; suppression tumor ... See more keywords