Oxidative degradation of pharmaceutical losartan potassium with N-doped hierarchical porous carbon and peroxymonosulfate
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.122971
Abstract: Abstract Losartan potassium (LOS) is a most globally consumed antihypertensive and emerging pharmaceutical contaminant of concern due to increasingly ubiquity in water and wastewater. For its effective environmental remediation, we propose the catalytic oxidation of… read more here.
Keywords: peroxymonosulfate; losartan potassium; porous carbon;
A clean photometric method for the determination of losartan potassium in pharmaceuticals exploiting light scattering effect and employing a multicommuted flow analysis approach.
Sign Up to like & getrecommendations! Published in 2017 at "Talanta"
DOI: 10.1016/j.talanta.2016.11.011
Abstract: This paper describes an environmentally friendly procedure for the determination of losartan potassium (Los-K) in pharmaceuticals. The photometric method was based on the light scattering effect due to particles suspension, which were formed by the… read more here.
Keywords: determination losartan; photometric method; determination; losartan potassium ... See more keywords
Formulation and Pharmacokinetic Evaluation of Ethyl Cellulose/HPMC-Based Oral Expandable Sustained Release Dosage of Losartan Potassium
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DOI: 10.1208/s12249-022-02295-9
Abstract: Prolonged retention of losartan potassium in the upper gastrointestinal tract is anticipated to increase its absorption and exposure to CYP450 enzyme subfamilies, undertaking its conversion to more potent (10–40 times) active metabolite, losartan carboxylic acid… read more here.
Keywords: formulation; ethyl cellulose; release; drug ... See more keywords
Meta-analysis of the effectiveness and safety of Shenyankangfu tablets combined with losartan potassium in the treatment of chronic glomerulonephritis
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DOI: 10.1371/journal.pone.0275735
Abstract: Objective To conduct a systematic review of the efficacy and safety of Shenyankangfu tablets in combination with losartan potassium in the treatment of chronic glomerulonephritis. Method We searched PubMed, Embase, Cochrane Library, CNKI, WanFang Data,… read more here.
Keywords: chronic glomerulonephritis; group; shenyankangfu tablets; losartan potassium ... See more keywords
Synthesis and Characterization of Nanoporous Carbon Carriers for Losartan Potassium Delivery
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DOI: 10.3390/ma14237345
Abstract: Losartan potassium is most commonly used for the treatment of hypertension. In recent years, new applications of this drug have emerged, encouraging the design of novel nanoporous carriers for its adsorption and release. The purpose… read more here.
Keywords: losartan potassium; release; synthesis characterization; potassium ... See more keywords
Preparation of Losartan Potassium Controlled Release Matrices and In-Vitro Investigation Using Rate Controlling Agents
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DOI: 10.3390/molecules27030864
Abstract: Controlled release matrices have predictable drug release kinetics, provide drugs for an extended period of time, and reduce dosing frequency with improved patient compliance as compared with conventional tablet dosage forms. In the current research… read more here.
Keywords: release matrices; controlled release; drug release; release ... See more keywords
Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa
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DOI: 10.3390/pharmaceutics14030570
Abstract: Epidermolysis bullosa is a genetically heterogenous skin fragility disorder with multiorgan involvement appearing already in newborn children. Severe progressive fibrosis follows skin blistering, mucosa lesions, and wound healing, favouring development of highly aggressive squamous cell… read more here.
Keywords: mini tablets; development; epidermolysis bullosa; coated mini ... See more keywords
Hydrochlorothiazide/Losartan Potassium Tablet Prepared by Direct Compression
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DOI: 10.3390/pharmaceutics14081741
Abstract: Hydrochlorothiazide (HCTZ)/losartan potassium (LOS-K) was used as a model drug to prepare compound tablets through the investigation of the compression and mechanical properties of mixed powders to determine the formulation and preparation factors, followed by… read more here.
Keywords: compression; tablet; mixed powder; losartan potassium ... See more keywords
Degradation of Losartan Potassium Highlighted by Correlated Studies of Photoluminescence, Infrared Absorption Spectroscopy and Dielectric Spectroscopy
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DOI: 10.3390/pharmaceutics14112419
Abstract: In this paper, new results on the degradation of losartan potassium (LP, (1)), in the absence and presence of excipients, which was induced by UV light, the acid character of phosphate buffer solution (PBS) and… read more here.
Keywords: photoluminescence; spectroscopy; degradation losartan; degradation ... See more keywords
Design and Evaluation of Losartan Potassium Effervescent Floating Matrix Tablets: In Vivo X-ray Imaging and Pharmacokinetic Studies in Albino Rabbits
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DOI: 10.3390/polym13203476
Abstract: Losartan potassium (LP) is an angiotensin receptor blocker used to treat hypertension. At higher pH, it shows poor aqueous solubility, which leads to poor bioavailability and lowers its therapeutic effectiveness. The main aim of this… read more here.
Keywords: losartan potassium; effervescent floating; ray imaging; effervescent ... See more keywords