Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2205626119
Abstract: Significance The β3-adrenergic receptor (β3-AR) is a major regulator of energy expenditure that triggers lipolysis and thermogenesis in adipose tissue, thereby significantly attenuating the risk of obesity. Obesity is associated with diminished β3-AR expression and… read more here.
Keywords: adipose tet; loss adipose; expression; tet proteins ... See more keywords
Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia
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DOI: 10.7554/elife.85103
Abstract: Chronically high blood glucose (hyperglycemia) leads to diabetes and fatty liver disease. Obesity is a major risk factor for hyperglycemia, but the underlying mechanism is unknown. Here, we show that a high-fat diet (HFD) in… read more here.
Keywords: induced loss; loss; loss adipose; adipose tissue ... See more keywords