Diagnosing and Preventing Hearing Loss in the Genomic Age
Sign Up to like & getrecommendations! Published in 2019 at "Trends in Hearing"
DOI: 10.1177/2331216519878983
Abstract: Over the past two decades, significant technological advances have facilitated the identification of hundreds of genes associated with hearing loss. Variants in many of these genes result in severe congenital hearing loss with profound implications… read more here.
Keywords: loss genomic; hearing loss; preventing hearing; diagnosing preventing ... See more keywords
Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart
Sign Up to like & getrecommendations! Published in 2019 at "EMBO reports"
DOI: 10.15252/embr.201847407
Abstract: Cardiac dysfunctions dramatically increase with age. Revealing a currently unknown contributor to cardiac ageing, we report the age‐dependent, cardiac‐specific accumulation of the lysosphingolipid sphinganine (dihydrosphingosine, DHS) as an evolutionarily conserved hallmark of the aged vertebrate… read more here.
Keywords: loss genomic; heart; integrity induced; induced lysosphingolipid ... See more keywords