Structural Rearrangements Maintain the Glycan Shield of an HIV-1 Envelope Trimer After the Loss of a Glycan
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DOI: 10.1038/s41598-018-33390-2
Abstract: The HIV-1 envelope (Env) glycoprotein is the primary target of the humoral immune response and a critical vaccine candidate. However, Env is densely glycosylated and thereby substantially protected from neutralisation. Importantly, glycan N301 shields V3… read more here.
Keywords: structural rearrangements; hiv envelope; rearrangements maintain; glycan shield ... See more keywords