Loss of legumain induces premature senescence and mediates aging‐related renal fibrosis
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DOI: 10.1111/acel.13574
Abstract: Aging is an independent risk factor for acute kidney injury and subsequent chronic kidney diseases, while the underlying mechanism is still elusive. Here, we found that renal tubules highly express a conserved lysosomal endopeptidase, legumain,… read more here.
Keywords: legumain; loss legumain; senescence; legumain deficiency ... See more keywords