Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination
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DOI: 10.1158/1541-7786.mcr-18-1335
Abstract: The combined loss of CHD1 and MAP3K7 promotes aggressive prostate cancer by unknown mechanisms. Because both of these genes are lost genetically in prostate cancer, they cannot be directly targeted. We applied an established computational… read more here.
Keywords: map3k7; loss map3k7; prostate cancer; cancer ... See more keywords