Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation
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DOI: 10.1016/j.celrep.2021.108913
Abstract: SUMMARY Prdm12 is a key transcription factor in nociceptor neurogenesis. Mutations of Prdm12 cause congenital insensitivity to pain (CIP) from failure of nociceptor development. However, precisely how deletion of Prdm12 during development or adulthood affects… read more here.
Keywords: causes defects; prdm12; pain sensation; loss prdm12 ... See more keywords