Loss of PRDX1 increases RAD51 Cys319 oxidation and decreases homologous recombination
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DOI: 10.1016/j.freeradbiomed.2018.10.159
Abstract: Peroxiredoxin 1 (PRDX1) is an oxidative stress protein sensor, which can coordinate cell signaling of its binding partners. Loss of Prdx1 function in mice has been shown to enhance susceptibility to various cancers, including breast… read more here.
Keywords: loss prdx1; oxidation; homologous recombination; prdx1 ... See more keywords