Articles with "loss predictor" as a keyword



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Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse

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Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-26489-0

Abstract: Driver gene mutations that are more prevalent in metastatic, castration-resistant prostate cancer (mCRPC) than localized disease represent candidate prognostic biomarkers. We analyze 1,844 localized (1,289) or mCRPC (555) tumors and quantify the prevalence of 113… read more here.

Keywords: prostate; loss predictor; somatic driver; znrf3 loss ... See more keywords