Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.04.041
Abstract: Retarded growth and neurodegeneration are hallmarks of the premature aging disease Cockayne syndrome (CS). Cockayne syndrome proteins take part in the key step of ribosomal biogenesis, transcription of RNA polymerase I. Here, we identify a… read more here.
Keywords: cockayne syndrome; rna polymerase; pathomechanism; loss proteostasis ... See more keywords