Loss of PTEN expression as diagnostic marker of endometrial precancer: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2019 at "Acta Obstetricia et Gynecologica Scandinavica"
DOI: 10.1111/aogs.13513
Abstract: Endometrial hyperplasia may be either a benign proliferation or a premalignant lesion. In order to differentiate these two conditions, two possible histologic classifications can be used: the World Health Organization (WHO) classification and the endometrial… read more here.
Keywords: diagnostic marker; marker endometrial; pten expression; loss pten ... See more keywords
Loss of PTEN promotes formation of signaling-capable clathrin-coated pits
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Science"
DOI: 10.1242/jcs.208926
Abstract: ABSTRACT Defective endocytosis and vesicular trafficking of signaling receptors has recently emerged as a multifaceted hallmark of malignant cells. Clathrin-coated pits (CCPs) display highly heterogeneous dynamics on the plasma membrane where they can take from… read more here.
Keywords: coated pits; clathrin coated; loss pten; signaling capable ... See more keywords
Loss of PTEN in Fallopian Tube Epithelium Results in Multicellular Tumor Spheroid Formation and Metastasis to the Ovary
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11060884
Abstract: High-grade serous ovarian cancer (HGSOC) can originate in the fallopian tube and then spread to the ovary. Our objective was to evaluate the role of multicellular tumor spheroids (MTS) in ovarian metastasis. By testing a… read more here.
Keywords: fallopian tube; multicellular tumor; formation; loss pten ... See more keywords
Prognostic Relevance and In Vitro Targeting of Concomitant PTEN and p16 Deficiency in Chordomas
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DOI: 10.3390/cancers15071977
Abstract: Simple Summary Chordomas are rare malignant bone tumors that predominantly occur along the spine. The most frequent alterations include the loss of PTEN and p16 proteins. While both oncoproteins have been investigated as independent prognostic… read more here.
Keywords: loss pten; p16 deficiency; pten p16; chordomas ... See more keywords