Excretion of excess nitrogen and increased survival by loss of SLC6A19 in a mouse model of ornithine transcarbamylase deficiency
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DOI: 10.1002/jimd.12568
Abstract: Protein catabolism ultimately yields toxic ammonia, which must be converted to urea by the liver for renal excretion. In extrahepatic tissues, ammonia is temporarily converted primarily to glutamine for subsequent hepatic extraction. Urea cycle disorders… read more here.
Keywords: slc6a19; excretion; deficiency; loss slc6a19 ... See more keywords