Articles with "low bioavailability" as a keyword



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Oral peptide delivery: Translational challenges due to physiological effects

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Published in 2018 at "Journal of Controlled Release"

DOI: 10.1016/j.jconrel.2018.08.032

Abstract: Abstract Oral delivery of peptide therapeutics as a convenient alternate to injections has been an area of research for the pharmaceutical scientific community for the last several decades. However, systemic delivery of therapeutic peptides via… read more here.

Keywords: delivery; peptide delivery; variability; oral peptide ... See more keywords
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Curcumin-3,4-Dichloro Phenyl Pyrazole (CDPP) overcomes curcumin's low bioavailability, inhibits adipogenesis and ameliorates dyslipidemia by activating reverse cholesterol transport.

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Published in 2017 at "Metabolism: clinical and experimental"

DOI: 10.1016/j.metabol.2017.05.005

Abstract: BACKGROUND Adipocyte dysfunction, obesity and associated metabolic disorders are of prime healthcare concern worldwide. Among available medications, natural products and inspired molecules hold 40% space in clinically prescribed medicines. In queue, this study overcomes the… read more here.

Keywords: reverse cholesterol; curcumin low; cdpp; bioavailability ... See more keywords