Low and constant micafungin concentrations may be sufficient to lead to resistance mutations in FKS2 gene of Candida glabrata.
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DOI: 10.1093/mmy/myx124
Abstract: We studied the ability of five echinocandin-susceptible C. glabrata isolates to acquire in vitro resistance to anidulafungin and micafungin. All isolates became phenotypically resistant after 2-4 days of exposure to low and constant micafungin concentrations… read more here.
Keywords: micafungin; micafungin concentrations; constant micafungin; low constant ... See more keywords