Articles with "low evolvability" as a keyword



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Greedy reduction of Bacillus subtilis genome yields emergent phenotypes of high resistance to a DNA damaging agent and low evolvability

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Published in 2023 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkad145

Abstract: Abstract Genome-scale engineering enables rational removal of dispensable genes in chassis genomes. Deviating from this approach, we applied greedy accumulation of deletions of large dispensable regions in the Bacillus subtilis genome, yielding a library of… read more here.

Keywords: evolvability; subtilis genome; bacillus subtilis; high resistance ... See more keywords