Low expression of exosomal miR-150 predicts poor prognosis in colorectal cancer patients after surgical resections.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac059
Abstract: Liver metastasis is a leading indicator of poor prognosis in patients with colorectal cancer (CRC). Exosomal intercellular communication has been reported to play an important role in cancer invasion and metastasis. Here, we characterized exosomal… read more here.
Keywords: expression exosomal; low expression; exosomal mir; mir 150 ... See more keywords
DNMT3A/3B overexpression might be correlated with poor patient survival, hypermethylation and low expression of ESR1/PGR in endometrioid carcinoma: an analysis of The Cancer Genome Atlas
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000000054
Abstract: Background: DNA methylation is involved in numerous biologic events and associates with transcriptional gene silencing, playing an important role in the pathogenesis of endometrial cancer. ESR1/PGR frequently undergoes de novo methylation and loss expression in… read more here.
Keywords: expression; esr1 pgr; overexpression; low expression ... See more keywords
Low expression of nm23-H1 associates with poor survival of nasopharyngeal carcinoma patients
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000007153
Abstract: Background: Developing a new reliable prognostic marker to predict the prognosis and supply better and more suitable therapy for patients with nasopharyngeal carcinoma (NPC) is urgent. Therefore, we performed this systematic review of the literature… read more here.
Keywords: prognosis; expression; nasopharyngeal carcinoma; expression nm23 ... See more keywords
Low expression of miR‐204 is associated with expression of CD34 and poor performance status in denovo AML
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.13161
Abstract: Acute myeloid leukemia (AML) is the most common acute leukemia in adults. There is growing evidence that microRNAs (miRNAs) provide prognostic information in AML. MiR‐204 has a tumor suppressor function, and several studies have proven… read more here.
Keywords: expression; mir 204; aml; low expression ... See more keywords
Low Expression of GLIS2 Gene Might Associate with Radiosensitivity of Gastric Cancer
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DOI: 10.1155/2019/2934925
Abstract: Human gene GLIS family zinc finger 2 (GLIS2) is a member of GLI-similar zinc finger protein family. Previous studies indicated GLIS2 gene involved in tumorigenesis mechanisms. However, the association between GLIS2 expression and radiosensitivity of… read more here.
Keywords: gastric cancer; expression glis2; expression; low expression ... See more keywords
Low expression of gamma-glutamyl transpeptidase 1 is an independent poor prognostic factor in ovarian clear cell carcinoma, in relation to up-regulation of immune suppressive genes and EMT-related genes.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.6042
Abstract: 6042Background: Ovarian clear cell carcinoma (OCCC) is a distinct entity from other epithelial ovarian cancers such as the most prevalent high-grade serous cancer (HGSC), and often exhibit less sen... read more here.
Keywords: cell carcinoma; low expression; clear cell; ovarian clear ... See more keywords
Low expression of microRNA-195 is a poor prognostic marker for ER-positive breast cancer patients.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.e12576
Abstract: e12576 Background: MicroRNA-195 (miR-195) is a tumor suppressive microRNA in breast cancer; however, its clinical relevance remains debatable because most data is either in vitro or from small cohort studies. In this study, we hypothesized that… read more here.
Keywords: mir 195; breast cancer; low expression; cancer ... See more keywords
Machine learning-based microarray analyses indicate low-expression genes might collectively influence PAH disease
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1007264
Abstract: Accurately predicting and testing the types of Pulmonary arterial hypertension (PAH) of each patient using cost-effective microarray-based expression data and machine learning algorithms could greatly help either identifying the most targeting medicine or adopting other… read more here.
Keywords: based microarray; machine learning; expression genes; expression ... See more keywords
Low expression of Rap1GAP is associated with epithelial-mesenchymal transition (EMT) and poor prognosis in gastric cancer
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DOI: 10.18632/oncotarget.14074
Abstract: Rap1GAP is a crucial tumor suppressor, but its role in gastric cancer (GC) is little investigated. In this study, we found that the expression of Rap1GAP was decreased in GC. Low expression of Rap1GAP was… read more here.
Keywords: expression rap1gap; poor prognosis; rap1gap; expression ... See more keywords
Low expression of SerpinB2 is associated with reduced survival in lung adenocarcinomas
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DOI: 10.18632/oncotarget.21456
Abstract: Lung cancer is a leading cause of cancer deaths worldwide and new biomarkers are of utmost importance. Studies have indicated that the anti-plasminogen activators SerpinB2 and Neuroserpin, and the adhesion molecule L1CAM, have a coordinated… read more here.
Keywords: serpinb2 associated; serpinb2; expression serpinb2; low expression ... See more keywords
Low expression of citron kinase is associated with poor patient outcomes in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Translational cancer research"
DOI: 10.21037/tcr.2020.03.58
Abstract: Hepatocellular carcinoma (HCC) is the sixth most common tumor type and the third leading cause of death related to cancer worldwide (1). Up to half of all HCC cases occur in China, and there were… read more here.
Keywords: hepatocellular carcinoma; expression citron; cancer; liver cancer ... See more keywords