Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.1292
Abstract: Importance Dose-reduced regimens of direct oral anticoagulants (DOACs) may be used for 2 main purposes: dose-adjusted treatment intended as full-intensity anticoagulation (eg, for stroke prevention in atrial fibrillation [AF] in patients requiring dose reduction) or… read more here.
Keywords: dose adjusted; low intensity; treatment; dose reduced ... See more keywords
Effect of Pulsed Low-Intensity Ultrasonography on Symptom Relief and Tibiofemoral Articular Cartilage Thickness Among Veterans Affairs Enrollees With Knee Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.0632
Abstract: Key Points Question Does 48 weeks of pulsed low-intensity ultrasonography (PLIUS) provide therapeutic benefit for patients with idiopathic knee osteoarthritis? Findings In this randomized clinical trial of 132 adults with symptomatic and radiographic idiopathic knee… read more here.
Keywords: intensity ultrasonography; cartilage thickness; cartilage; low intensity ... See more keywords
Low-Intensity Online Intervention for Mental Distress Among Help-Seeking Young People in Hong Kong
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.54675
Abstract: Key Points Question What are the effects of a low-intensity online intervention in community young people with at least moderate mental distress? Findings In this randomized clinical trial of 120 young people in Hong Kong,… read more here.
Keywords: low intensity; intervention; intensity online; online intervention ... See more keywords
Very Low‐Intensity Ultrasound Facilitates Glymphatic Influx and Clearance via Modulation of the TRPV4‐AQP4 Pathway
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202401039
Abstract: Recently, the glymphatic system has been proposed as a mechanism for waste clearance from the brain parenchyma. Glymphatic dysfunction has previously been shown to be associated with several neurological diseases, including Alzheimer's disease, traumatic brain… read more here.
Keywords: intensity ultrasound; brain; low intensity; glymphatic influx ... See more keywords
Low‐intensity focused ultrasound, a novel approach to epilepsy treatment in developing countries
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2852
Abstract: Approximately 80% of patients with epilepsy reside in poor resource settings. Despite the continued advancements and development of new treatment approaches, epilepsy remains a major health problem in developing countries. Consistent findings of epidemiologic studies… read more here.
Keywords: focused ultrasound; developing countries; low intensity; epilepsy ... See more keywords
Low Intensity Thermal Stimulation to Enhance Early Osteointegration in Implants: A Preclinical Study in Rabbits
Sign Up to like & getrecommendations! Published in 2025 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.70223
Abstract: ABSTRACT Objectives This study is the first to integrate 3D finite element modeling, in vitro validation, and preclinical animal experiments to determine the efficacy of low‐intensity thermal stimulation (LITS) in enhancing dental implant osseointegration. The… read more here.
Keywords: low intensity; thermal stimulation; osseointegration; intensity thermal ... See more keywords
Ecological response hides behind the species abundance distribution: Community response to low‐intensity disturbance in managed grasslands
Sign Up to like & getrecommendations! Published in 2017 at "Ecology and Evolution"
DOI: 10.1002/ece3.3395
Abstract: Abstract Land‐use and management are disturbance factors that have diverse effects on community composition and structure. In traditional rural grasslands, such as meadows and pastures, low‐intensity management is maintained to enhance biodiversity. Maintenance of road… read more here.
Keywords: response; intensity disturbance; intensity; sad shape ... See more keywords
Dynamic characteristics of T2* ‐weighted signal in calf muscles of peripheral artery disease during low‐intensity exercise
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25532
Abstract: To evaluate the dynamic characteristics of T2* ‐weighted signal change in exercising skeletal muscle of healthy subjects and peripheral artery disease (PAD) patients under a low‐intensity exercise paradigm. read more here.
Keywords: weighted signal; peripheral artery; dynamic characteristics; characteristics weighted ... See more keywords
Prolonged stimulation with low‐intensity ultrasound induces delayed increases in spontaneous hippocampal culture spiking activity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.23845
Abstract: Ultrasound is a promising neural stimulation modality, but an incomplete understanding of its range and mechanism of effect limits its therapeutic application. We investigated the modulation of spontaneous hippocampal spike activity by ultrasound at a… read more here.
Keywords: stimulation low; stimulation; intensity; spontaneous hippocampal ... See more keywords
Inhibitory Effect of Low‐Intensity Pulsed Ultrasound on the Expression of Lipopolysaccharide‐Induced Inflammatory Factors in U937 Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Ultrasound in Medicine"
DOI: 10.1002/jum.14239
Abstract: Low‐intensity pulsed ultrasound (US) has been reported to promote periodontal tissue regeneration and reduce inflammation in soft tissues and in bone infectious diseases. Here we investigated the effect of low‐intensity pulsed US on the expression… read more here.
Keywords: effect low; pulsed ultrasound; expression lipopolysaccharide; low intensity ... See more keywords
Effects of Low‐Intensity Pulsed Ultrasound Therapy on the Temporomandibular Joint Complex in Conjunction With a Fixed Functional Appliance: A Prospective 3‐Dimensional Cone Beam Computed Tomographic Study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ultrasound in Medicine"
DOI: 10.1002/jum.14850
Abstract: This prospective study aimed to analyze 3‐dimensional changes in the temporomandibular joint (TMJ) complex with a synergistic effect of functional jaw orthopedics using a fixed functional appliance and low‐intensity pulsed ultrasound (LIPUS) therapy. read more here.
Keywords: pulsed ultrasound; temporomandibular joint; fixed functional; functional appliance ... See more keywords