Robust differential expression testing for single-cell CRISPR screens at low multiplicity of infection
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DOI: 10.1186/s13059-024-03254-2
Abstract: Single-cell CRISPR screens (perturb-seq) link genetic perturbations to phenotypic changes in individual cells. The most fundamental task in perturb-seq analysis is to test for association between a perturbation and a count outcome, such as gene… read more here.
Keywords: cell crispr; multiplicity infection; single cell; low multiplicity ... See more keywords