From DC18 to MR07: A Metabolically Stable 4,4′‐Oxybisbenzoyl Amide as a Low‐Nanomolar Growth Inhibitor of P. falciparum
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DOI: 10.1002/cmdc.202200355
Abstract: To improve the metabolic stability of a 4,4′‐oxybisbenzoyl‐based novel and potent (nanomolar‐range IC50) antiplasmodial agent previously described by us, in silico‐guided structure‐activity relationship (SAR) campaigns have been conducted to substitute its peptide decorations with more… read more here.
Keywords: oxybisbenzoyl amide; metabolically stable; mr07 metabolically; dc18 mr07 ... See more keywords