CasSABER for Programmable In Situ Visualization of Low and Nonrepetitive Gene Loci.
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DOI: 10.1021/acs.analchem.2c04867
Abstract: Site-specific imaging of target genes using CRISPR probes is essential for understanding the molecular mechanisms of gene function and engineering tools to modulate its downstream pathways. Herein, we develop CRISPR/Cas9-mediated signal amplification by exchange reaction… read more here.
Keywords: nonrepetitive gene; cassaber programmable; low nonrepetitive; gene loci ... See more keywords