A gene expression-based classifier for HER2-low breast cancer
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DOI: 10.1038/s41598-024-52148-7
Abstract: In clinical trials evaluating antibody-conjugated drugs (ADCs), HER2-low breast cancer is defined through protein immunohistochemistry scoring (IHC) 1+ or 2+ without gene amplification. However, in daily practice, the accuracy of IHC is compromised by inter-observer variability. Herein,… read more here.
Keywords: gene expression; her2; her2 low; low signature ... See more keywords