Acid-Directed Electrostatic Self-Assembly Generates Charge-Reversible Bacteria for Enhanced Tumor Targeting and Low Tissue Trapping.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c08684
Abstract: Despite recent preclinical progress with oncolytic bacteria in cancer therapy, dose-limiting toxicity has been a long-standing challenge for clinical application. Genetic and chemical modifications for enhancing the bacterial tumor-targeting ability have been unable to establish… read more here.
Keywords: self assembly; tumor targeting; tissue trapping; low tissue ... See more keywords
Low Tissue Creatine: A Therapeutic Target in Clinical Nutrition
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DOI: 10.3390/nu14061230
Abstract: Low tissue creatine characterizes many conditions, including neurodegenerative, cardiopulmonary, and metabolic diseases, with a magnitude of creatine shortfall often corresponds well to a disorder’s severity. A non-invasive monitoring of tissue metabolism with magnetic resonance spectroscopy… read more here.
Keywords: target clinical; tissue creatine; creatine; clinical nutrition ... See more keywords