Antimicrobial Nanostructured Assemblies with Extremely Low Toxicity and Potent Activity to Eradicate Staphylococcus Aureus Biofilms.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202204039
Abstract: Self-assembled cationic polymeric nanostructures have been receiving increasing attention for efficient antibacterial agents. In this work, a new type of antibacterial agents is developed by preparing pH-dependent nanostructured assemblies from cationic copolypeptoid poly(N-allylglycine)-b-poly(N-octylglycine) (PNAG-b-PNOG) modified… read more here.
Keywords: pnog; low toxicity; extremely low; staphylococcus aureus ... See more keywords
Evaluation of a Low-Toxicity PARP Inhibitor as a Neuroprotective Agent for Parkinson's Disease.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02371-4
Abstract: Repurposing PARP-1 inhibitors (PARPi) for non-oncological applications offers an attractive therapeutic strategy for pathological conditions characterized by PARP-1 hyperactivity. In the context of Parkinson's disease (PD), PARP-1 hyperactivity has been linked to neuronal death and… read more here.
Keywords: low toxicity; disease; toxicity; evaluation ... See more keywords
Evolution of Pb-Free and Partially Pb-Substituted Perovskite Absorbers for Efficient Perovskite Solar Cells
Sign Up to like & getrecommendations! Published in 2019 at "Electronic Materials Letters"
DOI: 10.1007/s13391-019-00149-4
Abstract: Announced as one of the top 10 research breakthroughs in 2016, perovskite solar cells (PSC) have advanced rapidly as an established photovoltaic technology. The power conversion efficiency (PCE) of PSCs has increased quickly from 3.8%… read more here.
Keywords: perovskite solar; perovskite absorbers; low toxicity; toxicity ... See more keywords
Novel tetranuclear ruthenium(II) arene complexes showing potent cytotoxic and antimetastatic activity as well as low toxicity in vivo.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.06.061
Abstract: Ruthenium complexes have attracted a surge of interest as anticancer drug candidates because of their low toxicity, diversity in mode-of-actions and non-cross drug resistance with conventional platinum-based agents. Despite remarkable advances, only a limited number… read more here.
Keywords: ruthenium; low toxicity; cancer; antimetastatic activity ... See more keywords
Sclerotiorin stabilizes the assembly of non-fibrillar Abeta42 oligomers with low toxicity, seeding activity and beta-sheet content.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.01.033
Abstract: The self-assembly of the 42-residue amyloid-β peptide, Aβ42, into fibrillar aggregates is associated with neuronal dysfunction and toxicity in Alzheimer's disease (AD) patient brains, suggesting that small molecules acting on this process might interfere with… read more here.
Keywords: sheet content; low toxicity; seeding activity; sheet ... See more keywords
Exploring Low-Toxicity Chemical Space with Deep Learning for Molecular Generation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c00671
Abstract: Creating a wide range of new compounds that not only have ideal pharmacological properties but also easily pass long-term toxicity evaluation is still a challenging task in current drug discovery. In this study, we developed… read more here.
Keywords: low toxicity; toxicity; generation; diversity ... See more keywords
Cerium–Bismuth Oxides/Oxynitrates with Low Toxicity for the Removal and Degradation of Organophosphates and Bisphenols
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Nano Materials"
DOI: 10.1021/acsanm.2c03926
Abstract: Nanoscale cerium–bismuth oxides/oxynitrates were prepared by a scalable low-temperature method at ambient pressure using water as the sole solvent. Solid solutions were formed up to a 1:1 Ce/Bi molar ratio, while at higher doping levels,… read more here.
Keywords: bismuth oxides; low toxicity; removal; cerium bismuth ... See more keywords
Photoinduced Iron-Catalyzed ATRP of Renewable Monomers in Low-Toxicity Solvents: A Greener Approach
Sign Up to like & getrecommendations! Published in 2022 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.2c00302
Abstract: Producing polymers from renewable resources via more sustainable approaches has become increasingly important. Herein we present the polymerization of monomers obtained from biobased renewable resources, employing an environmentally friendly photoinduced iron-catalyzed atom transfer radical polymerization… read more here.
Keywords: low toxicity; photoinduced iron; renewable monomers; toxicity solvents ... See more keywords
Highly Ca2+-Ion-Tolerant Biobased Zwitterionic Surfactant with High Interfacial Activity
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04642
Abstract: The wide application of surfactants has a harmful effect on the environment, drawing more attention to the development and application of low-toxicity surfactants. A salt-tolerant and low-toxicity biobased zwitterionic surfactant, N,N-dimethyl-N-[2-hydroxy-3-sulfo-propyl]-N-benzyloxyoctadecanoyl-1,3-propanediamine (SPBOPA), was prepared from… read more here.
Keywords: surfactant; low toxicity; ca2 ion; highly ca2 ... See more keywords
Non-corrosive, low-toxicity gel-based microbattery from organic and organometallic molecules
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry A"
DOI: 10.1039/c9ta08685d
Abstract: The combination of natural hydrogel agarose and redox-active organic and organometallic molecules provides a non-corrosive, non-flammable and low-toxicity microbattery. read more here.
Keywords: low toxicity; microbattery; non corrosive; organic organometallic ... See more keywords
Investigation of the Burning Properties of Low-Toxicity B/CuO Delay Compositions
Sign Up to like & getrecommendations! Published in 2018 at "Combustion Science and Technology"
DOI: 10.1080/00102202.2018.1539968
Abstract: ABSTRACT This study explored the reaction characteristics and the burning properties of low-toxicity B/CuO delay compositions. Firstly, differential scanning calorimetry (DSC) and thermogravimetry (TG) were used to measure and analyze the reaction characteristics. Afterward the… read more here.
Keywords: cuo; burning properties; low toxicity; delay ... See more keywords