Telomerase inhibition is an effective therapeutic strategy in TERT promoter mutant-glioblastoma models with low tumor volume.
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DOI: 10.1093/neuonc/noad024
Abstract: BACKGROUND Glioblastoma is among the deadliest of all cancers, with 5-year survival rates of only 6%. Glioblastoma targeted therapeutics have been challenging to develop due to significant inter- and intra-tumoral heterogeneity. TERT promoter mutations are… read more here.
Keywords: glioblastoma; low tumor; tert promoter; telomerase inhibition ... See more keywords