Tracheal and lower airway changes in a patient with mucolipidosis type II
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24765
Abstract: Mucolipidosis type II (MLII) is a lysosomal storage disease causing systemic deposition of mucopolysaccharides. We describe imaging and bronchoscopy findings not previously reported in the literature in a child with MLII. read more here.
Keywords: tracheal lower; lower airway; mucolipidosis; mucolipidosis type ... See more keywords
Association of upper and lower airway eosinophilic inflammation with response to omalizumab in patients with severe asthma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Asthma"
DOI: 10.1080/02770903.2018.1541357
Abstract: Abstract Background: The anti-immunoglobulin E monoclonal antibody, omalizumab, is used to treat severe asthma and has the potential to ameliorate airway inflammation. However, the effect of omalizumab in ameliorating upper airway inflammation has not been… read more here.
Keywords: response; omalizumab; severe asthma; inflammation ... See more keywords
Predicting the likelihood of lower respiratory tract Ureaplasma infection in preterms
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2022-324192
Abstract: Objective To develop predictive models of Ureaplasma spp lower airway tract infection in preterm infants. Methods A dataset was assembled from five cohorts of infants born 72 hours were significant predictors in all 3 models.… read more here.
Keywords: laboratory values; infection; ureaplasma infection; likelihood lower ... See more keywords
The lower airway microbiota in early cystic fibrosis lung disease: a longitudinal analysis
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DOI: 10.1136/thoraxjnl-2016-209279
Abstract: Rationale In infants and young children with cystic fibrosis, lower airway infection and inflammation are associated with adverse respiratory outcomes. However, the role of lower airway microbiota in the pathogenesis of early cystic fibrosis lung… read more here.
Keywords: airway microbiota; cystic fibrosis; lower airway; age ... See more keywords
Mechanism of Lower Airway Hyperresponsiveness Induced by Allergic Rhinitis
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DOI: 10.1155/2022/4351345
Abstract: Allergic rhinitis is a global illness that puzzles many researchers. Most patients with allergic rhinitis also have lower airway hyperresponsiveness, and an allergic rhinitis attack can increase lower airway hyperresponsiveness. However, the mechanism of the… read more here.
Keywords: airway hyperresponsiveness; rhinitis; lower airway; mechanism ... See more keywords
Lower Airway Inflammation in Eosinophilic Chronic Rhinosinusitis as Determined by Exhaled Nitric Oxide
Sign Up to like & getrecommendations! Published in 2017 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000479387
Abstract: Background: Chronic rhinosinusitis (CRS) is classified into eosinophilic CRS (ECRS) and non-ECRS. The objectives of this study were to evaluate lower airway inflammation by measuring the fractional concentration of exhaled nitric oxide (FeNO) and to… read more here.
Keywords: non ecrs; lower airway; chronic rhinosinusitis; airway inflammation ... See more keywords
Prospective case-control study describing the lower airway microbiome in pre-school children with cystic fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.oa509
Abstract: Introduction: The traditional paradigm that the lung is a sterile environment no longer holds true in the current era of the microbiome. Aim: Our aim was to describe the lower airway microbiome in pre-school children… read more here.
Keywords: microbiome pre; school children; pre school; diversity ... See more keywords
Lower airway pathology in children with Down syndrome compared to controls
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa1360
Abstract: Introduction: Children with Down syndrome (DS) often present with respiratory symptoms. Congenital airway anomalies have been described, but prevalence is scarce and a comparison to “healthy” controls is missing. Aim: To compare endoscopic and clinical… read more here.
Keywords: compared controls; lower airway; pathology; children syndrome ... See more keywords
Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping
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DOI: 10.1186/s12931-021-01619-w
Abstract: Background Elderly asthmatics represent an important group that is often excluded from clinical studies. In this study we wanted to present characteristics of asthmatics older than 70 years old as compared to younger patients. Methods We… read more here.
Keywords: air trapping; sputum; lower airway; variability ... See more keywords
Host transcriptomic signatures associated with dysbiosis in a preclinical model of lung cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.3107
Abstract: 3107 Background: Enrichment of the lower airway microbiota with oral commensals has been associated with transcriptomic changes affecting several inflammatory pathways associated with non-small cell lung cancer (NSCLC) development and progression. Using a mouse model… read more here.
Keywords: dysbiosis; lung cancer; cancer; lower airway ... See more keywords
Detection and identification of fungi in the lower airway of children with and without cystic fibrosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1119703
Abstract: Introduction Airway infection and inflammation lead to the progression of obstructive lung disease in persons with cystic fibrosis (PWCF). However, cystic fibrosis (CF) fungal communities, known drivers of CF pathophysiology, remain poorly understood due to… read more here.
Keywords: children without; rrna sequencing; ssu rrna; lower airway ... See more keywords