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   Articles with "lowering drugs" as a keyword



Association of Lipid-Lowering Drugs With Risk of Psoriasis: A Mendelian Randomization Study.

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recommendations! Published in 2023 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.6051

Abstract: Importance Lipid pathways have been implicated in the pathogenesis of psoriasis, and some lipid-lowering drugs, such as statins, are hypothesized to have disease-modifying properties. However, large population-level studies are scarce, and causal interpretation of results… read more here.

Keywords: lowering drugs; risk psoriasis; lipid lowering; risk ... See more keywords

The Pro12Ala polymorphism of PPARγ2 modulates beta cell function and failure to oral glucose‐lowering drugs in patients with type 2 diabetes

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recommendations! Published in 2020 at "Diabetes/Metabolism Research and Reviews"

DOI: 10.1002/dmrr.3392

Abstract: We evaluate whether the Pro12Ala polymorphism of peroxisome proliferator‐activated receptor γ2 (PPARγ2) has a role in the progression of diabetes by modulating the occurrence of treatment failure to glucose‐lowering drugs. read more here.

Keywords: ppar; failure; lowering drugs; pro12ala polymorphism ... See more keywords

Real world evidence of clinical predictors of glycaemic response to glucose‐lowering drugs among Chinese with type 2 diabetes

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recommendations! Published in 2023 at "Diabetes/Metabolism Research and Reviews"

DOI: 10.1002/dmrr.3615

Abstract: To examine whether simple clinical features can predict the 1‐year glycaemic response to glucose‐lowering drugs (GLDs) among Chinese with type 2 diabetes. read more here.

Keywords: lowering drugs; glucose lowering; among chinese; chinese type ... See more keywords

Newer glucose‐lowering drugs reduce the risk of late‐onset seizure and epilepsy: A meta‐analysis

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recommendations! Published in 2024 at "Epilepsia Open"

DOI: 10.1002/epi4.13091

Abstract: Newer glucose‐lowering drugs (GLDs) protect against cerebrovascular, neurodegenerative, and neuroinflammatory pathologies. Therefore, we performed a meta‐analysis of randomized controlled trials (RCTs) comparing newer GLDs to placebo that assessed long‐term cardiovascular and renal outcomes to analyze… read more here.

Keywords: risk; late onset; glucose lowering; lowering drugs ... See more keywords

Glycaemic Control and Vascular Complications in Diabetes Mellitus Type 2.

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recommendations! Published in 2020 at "Advances in experimental medicine and biology"

DOI: 10.1007/5584_2020_514

Abstract: Diabetes mellitus is constantly increasing worldwide. Vascular complications are the most common in the setting of long-standing disease, claiming the greatest burden in terms of morbidity and mortality. Glucotoxicity is involved in vascular damage through… read more here.

Keywords: control; glycaemic control; lowering drugs; diabetes mellitus ... See more keywords
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Glucose-Lowering Drugs and Fracture Risk—a Systematic Review

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recommendations! Published in 2020 at "Current Osteoporosis Reports"

DOI: 10.1007/s11914-020-00638-8

Abstract: Diabetes mellitus (DM) is associated with increased fracture risk. The aim of this systematic review was to examine the effects of different classes of glucose-lowering drugs on fracture risk in patients with type 2 DM.… read more here.

Keywords: drugs fracture; fracture; lowering drugs; fracture risk ... See more keywords

Effects of evolving lipid-lowering drugs on carbohydrate metabolism.

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recommendations! Published in 2018 at "Diabetes research and clinical practice"

DOI: 10.1016/j.diabres.2017.12.012

Abstract: The understanding that statins reduce but not eliminate the cardiovascular risk associated with disturbed lipid metabolism and the existence of forms of dyslipidemia that are unresponsive or only partially responsive to statins have led to… read more here.

Keywords: drugs carbohydrate; effects evolving; metabolism; lowering drugs ... See more keywords

Are current dietary guidelines relevant to subjects on cholesterol-lowering drugs?

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recommendations! Published in 2019 at "Proceedings of the Nutrition Society"

DOI: 10.1017/s0029665119000685

Abstract: The present paper reviews the evidence as to whether patients on lipid-lowering drugs should restrict dietary SFA intake. Premature mortality from atherosclerotic CVD has fallen dramatically in many high-income countries. This appears to be due… read more here.

Keywords: lowering drugs; sfa intake; cholesterol; dietary sfa ... See more keywords

Safety and tolerability of available urate-lowering drugs: a critical review

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recommendations! Published in 2019 at "Expert Opinion on Drug Safety"

DOI: 10.1080/14740338.2019.1594771

Abstract: ABSTRACT Introduction: Urate-lowering therapy (ULT) is the cornerstone of gout management, which is a widespread chronic illness characterized by hyperuricemia, arthropathy, tophus development, and urolithiasis. Since asymptomatic increased serum urate levels are associated with a… read more here.

Keywords: safety tolerability; safety; lowering drugs; urate lowering ... See more keywords

Glucose lowering drugs with proven cardiovascular benefit following acute coronary syndrome in type 2 diabetes: treatment gaps and outcomes

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recommendations! Published in 2024 at "European Heart Journal"

DOI: 10.1093/eurheartj/ehae666.2930

Abstract: Real-world data on the implementation and prognostic impact of glucose-lowering drugs with proven cardiovascular benefits in patients with type 2 diabetes (T2D) following acute coronary syndromes (ACS) is limited. We investigated the utilization and treatment… read more here.

Keywords: drugs proven; treatment; type diabetes; glucose lowering ... See more keywords

4113Glucose lowering drugs or strategies, major adverse cardiovascular events and heart failure outcomes, and association with weight loss - meta-analysis of large cardiovascular outcome trials

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recommendations! Published in 2019 at "European Heart Journal"

DOI: 10.1093/eurheartj/ehz745.0117

Abstract: Glucose lowering drugs or strategies (GLDS) have varied effects on major adverse cardiovascular events (MACE) and heart failure (HF) in cardiovascular outcomes trials. Mechanisms driving cardiovascular risk reduction remain elusive. We searched MEDLINE, PubMed, and… read more here.

Keywords: heart; heart failure; lowering drugs; cardiovascular ... See more keywords