Strategic Lowering of LDL-cholesterol Post Ischemic Stroke: Identifying Optimal Targets, Timing, and Therapeutic Approaches
Sign Up to like & getrecommendations! Published in 2025 at "Thrombosis and Haemostasis"
DOI: 10.1055/a-2675-0551
Abstract: Abstract Stroke remains a leading cause of morbidity and mortality worldwide, with ischemic stroke dominating the landscape. Dyslipidemia, particularly elevated low-density lipoprotein cholesterol (LDL-C), is a critical modifiable risk factor in both primary and secondary… read more here.
Keywords: strategic lowering; ischemic stroke; stroke; ldl cholesterol ... See more keywords
PCSK9 Inhibitors: Mechanisms of Action, Metabolic Effects, and Clinical Outcomes.
Sign Up to like & getrecommendations! Published in 2018 at "Annual review of medicine"
DOI: 10.1146/annurev-med-042716-091351
Abstract: Atherosclerotic cardiovascular disease (ASCVD) is associated with significant morbidity and mortality worldwide. Increased serum levels of low-density lipoprotein cholesterol (LDL-C) are an independent risk factor for ASCVD, and clinical trial data have shown that lowering… read more here.
Keywords: pcsk9 inhibitors; lowering ldl; clinical outcomes; effects clinical ... See more keywords