Pharmacological evaluation and molecular docking of new di‐tert‐butylphenol compound, LQFM‐091, a new dual 5‐LOX/COX inhibitor
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.06.006
Abstract: Abstract Dual 5‐LOX/COX inhibitors are potential new dual drugs to treat inflammatory conditions. This research aimed to design, synthesis and to evaluate the anti‐inflammatory and antinociceptive effects of the new compound, which is derived from… read more here.
Keywords: lox cox; lox; new dual; compound ... See more keywords
A novel class of tyrosine derivatives as dual 5-LOX and COX-2/mPGES1 inhibitors with PGE2 mediated anticancer properties
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DOI: 10.1039/c8nj04385j
Abstract: Leukotriene and prostaglandin pathways are controlled by the enzymes, LOX and COX/mPGES1 respectively and are responsible for inflammatory responses. read more here.
Keywords: cox mpges1; class tyrosine; novel class; lox cox ... See more keywords