Up-regulation of long non-coding RNA LOXL1-AS1 functions as an oncogene in cervical squamous cell carcinoma by sponging miR-21.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2020.1804406
Abstract: LncRNA LOXL1-AS1 has been reported to be upregulated in several types of cancer and plays oncogenic roles. We analysed TCGA dataset and observed the downregulation of LOXL1-AS1 in cervical squamous cell carcinoma (CSCC). We therefore… read more here.
Keywords: squamous cell; loxl1; loxl1 as1; cervical squamous ... See more keywords
LOXL1-AS1/miR-515-5p/STAT3 positive feedback loop facilitates cell proliferation and migration in atherosclerosis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000853
Abstract: Existing research has elucidated the critical role of long noncoding RNAs (lncRNAs) in the progression of multiple human cardiovascular diseases, including atherosclerosis (AS). Nonetheless, whether lncRNA LOXL1 antisense RNA 1 (LOXL1-AS1) regulates the biological functions… read more here.
Keywords: huvecs; loxl1; mir 515; loxl1 as1 ... See more keywords
LncRNA LOXL1-AS1 expression in cancer prognosis: A meta-analysis
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DOI: 10.1097/md.0000000000032436
Abstract: Background: Several studies showed that LncRNA LOXL1 antisense RNA 1 (LOXL1-AS1) is overexpressed in a variety of cancers and plays a role as an oncogene in cancer. The present meta-analysis aims to elucidate the relationship… read more here.
Keywords: cancer; loxl1 as1; loxl1; as1 expression ... See more keywords
Cleavage of LOXL1 by BMP1 and ADAMTS14 Proteases Suggests a Role for Proteolytic Processing in the Regulation of LOXL1 Function
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23063285
Abstract: Members of the lysyl oxidase (LOX) family catalyze the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin in the initiation step of the formation of covalent cross-links, an essential process for connective… read more here.
Keywords: loxl1 function; regulation loxl1; bmp1 adamts14; loxl1 ... See more keywords