LncRNA LOXL1‐AS1/miR‐let‐7a‐5p/EGFR‐related pathway regulates the doxorubicin resistance of prostate cancer DU‐145 cells
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2075
Abstract: Our study aimed to investigate the effects of lncRNA LOXL1‐AS1/miR‐let‐7a‐5p/EGFR‐axis on prostate cancer (PCa) progression. Microarray analysis was conducted to determine differentially expressed lncRNAs and mRNAs. Gene Set Enrichment analysis was implemented for verification of… read more here.
Keywords: mir let; as1; loxl1 as1; prostate cancer ... See more keywords
Up-regulation of long non-coding RNA LOXL1-AS1 functions as an oncogene in cervical squamous cell carcinoma by sponging miR-21.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2020.1804406
Abstract: LncRNA LOXL1-AS1 has been reported to be upregulated in several types of cancer and plays oncogenic roles. We analysed TCGA dataset and observed the downregulation of LOXL1-AS1 in cervical squamous cell carcinoma (CSCC). We therefore… read more here.
Keywords: squamous cell; loxl1; loxl1 as1; cervical squamous ... See more keywords
The LOXL1 antisense RNA 1 (LOXL1-AS1)/microRNA-423-5p (miR-423-5p)/ectodermal-neural cortex 1 (ENC1) axis promotes cervical cancer through the mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2018975
Abstract: ABSTRACT As the fourth commonest malignancy among females worldwide, cervical cancer (CC) poses a huge challenge to human health. The pivotal regulatory roles of lncRNAs in cancers have been highlighted. LOXL1 antisense RNA 1 (LOXL1-AS1)… read more here.
Keywords: mir 423; loxl1 as1; kinase; 423 mir ... See more keywords
LOXL1-AS1/miR-515-5p/STAT3 positive feedback loop facilitates cell proliferation and migration in atherosclerosis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000853
Abstract: Existing research has elucidated the critical role of long noncoding RNAs (lncRNAs) in the progression of multiple human cardiovascular diseases, including atherosclerosis (AS). Nonetheless, whether lncRNA LOXL1 antisense RNA 1 (LOXL1-AS1) regulates the biological functions… read more here.
Keywords: huvecs; loxl1; mir 515; loxl1 as1 ... See more keywords
LncRNA LOXL1-AS1 expression in cancer prognosis: A meta-analysis
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DOI: 10.1097/md.0000000000032436
Abstract: Background: Several studies showed that LncRNA LOXL1 antisense RNA 1 (LOXL1-AS1) is overexpressed in a variety of cancers and plays a role as an oncogene in cancer. The present meta-analysis aims to elucidate the relationship… read more here.
Keywords: cancer; loxl1 as1; loxl1; as1 expression ... See more keywords
LncRNA LOXL1-AS1 inhibits proliferation of PDLSCs and downregulates IL-1β in periodontitis patients.
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DOI: 10.1111/jre.12962
Abstract: BACKGROUND The carcinogenic role of lncRNA LOXL1-AS1 in thoracic aortic aneurysm has been confirmed, but its role in the pathogenesis of periodontitis remains unclear. Our preliminary deep sequencing data revealed LOXL1-AS1 downregulation in periodontitis and… read more here.
Keywords: pdlscs; periodontitis; loxl1 as1; proliferation ... See more keywords
Abstract 1285: The pro-metastatic role of long-noncoding RNA LOXL1-AS1 in sonic-hedgehog medulloblastoma
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DOI: 10.1158/1538-7445.am2023-1285
Abstract: Introduction: Medulloblastoma (MB) is the most common malignant tumor in children. Since most MB-related deaths are the result of metastasis, current standard care for MB is aggressive with intense post-surgical radiotherapies, which aim to minimize… read more here.
Keywords: metastasis; shh; loxl1 as1; pro metastatic ... See more keywords
Study on the mechanism of LOXL1-AS1/miR-3614-5p/YY1 signal axis in the malignant phenotype regulation of hepatocellular carcinoma
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DOI: 10.1186/s13062-021-00312-8
Abstract: Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with high mortality worldwide. Accumulating researches have indicated that long non‑coding RNAs (lncRNAs) are involved in varies human cancers, including HCC. Nevertheless, the… read more here.
Keywords: hcc; loxl1 as1; 3614 yy1; mir 3614 ... See more keywords
LncRNA LOXL1-AS1 promotes esophageal squamous cell carcinoma progression by targeting DESC1
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DOI: 10.7150/jca.51136
Abstract: Recently, ample evidence indicated that numerous aberrantly expressed long non-coding RNAs (lncRNAs) participated in the development of multiple malignancies. However, the expression and function of lncRNA LOXL1-AS1 in mediating esophageal squamous cell carcinoma (ESCC) carcinogenesis… read more here.
Keywords: as1; cell carcinoma; squamous cell; loxl1 as1 ... See more keywords