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   Articles with "lpcat1" as a keyword



LPCAT1 enhances the invasion and migration in gastric cancer: Based on computational biology methods and in vitro experiments.

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recommendations! Published in 2023 at "Cancer medicine"

DOI: 10.1002/cam4.5991

Abstract: BACKGROUND AND AIM The biological functions and clinical implications of lysophosphatidylcholine acyltransferase 1 (LPCAT1) remain unclarified in gastric cancer (GC). The aim of the current study was to explore the possible clinicopathological significance of LPCAT1… read more here.

Keywords: lpcat1; migration; invasion; gastric cancer ... See more keywords
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ncRNA-Mediated High Expression of LPCAT1 Correlates with Poor Prognosis and Tumor Immune Infiltration of Liver Hepatocellular Carcinoma

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recommendations! Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/1584397

Abstract: Purpose To investigate the expression of LPCAT1 in liver hepatocellular carcinoma (LIHC) and its relationship with prognosis and immune infiltration and predict its upstream nonencoding RNAs (ncRNAs). Method In this study, expression analysis and survival… read more here.

Keywords: prognosis; lpcat1; immune infiltration; tumor immune ... See more keywords
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LPCAT1 enhances castration resistant prostate cancer progression via increased mRNA synthesis and PAF production

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recommendations! Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0240801

Abstract: Our previously study shown that Lysophosphatidylcholine Acyltransferase1 (LPCAT1) is overexpressed in castration resistant prostate cancer (CRPC) relative to primary prostate cancer (PCa), and androgen controls its expression via the Wnt signaling pathway. While highly expressed… read more here.

Keywords: lpcat1; mrna synthesis; prostate cancer; crpc ... See more keywords
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Lysophosphatidylcholine acyltransferase 1 protein is present in maternal blood in the third trimester and is upregulated by antenatal corticosteroids

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recommendations! Published in 2022 at "Journal of Perinatal Medicine"

DOI: 10.1515/jpm-2022-0150

Abstract: Abstract Objectives Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is involved in the production of fetal lung surfactant. We have shown that LPCAT1 mRNA is present in amniotic fluid and maternal plasma and that its quantity correlates with… read more here.

Keywords: lpcat1; maternal plasma; plasma; antenatal corticosteroids ... See more keywords
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Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating TGF-β/Smad2/3 signaling pathway

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recommendations! Published in 2022 at "Acta Biochimica et Biophysica Sinica"

DOI: 10.3724/abbs.2022076

Abstract: The incidence of endometrial cancer (EC) increases annually and tends to occur in younger women. A particularly important relationship exists between EC and metabolic disorders. As one of the most important components of lipid metabolism,… read more here.

Keywords: endometrial cancer; signaling pathway; lpcat1; tgf smad2 ... See more keywords